European settlers trickled in slowly until about 1820, when James Keyte, a Brunswick, England, native and
Methodist minister, built a cabin in Keytesville and in 1836 founded Brunswick. Here he spent the rest of his life,
serving variously as postmaster, merchant, builder, and steamboat line manager. He lured boatmen to Brunswick by giving them free land. 

The soil was rich. Trade in tobacco, grains, cotton, honey, pork and furs flourished. Tobacco factories sprang up.  James (Oz) Kelliker of Brunswick still has the forms used by his father to make cigars in the Kelliker factory. A brick factory used soil from what is known today as "clay cliff'. Part of one tobacco factory footing forms the retaining wall in front of Udell and Ruby Unternaehrer's home on Vine Street. The brick factory was south of the present railroad tracks.

The first church was the South Methodist. The present United Methodist Church, remodeled over the years, still has "South Methodist" etched on its transom. A North Methodist Church was soon established. Other churches quickly followed.

The first school, taught by Judge John M. Davis, was opened in June, 1840, for a five-month term. These early
schools required tuition.

The first German colony arrived in 1840. The first newspaper, The Brunswicker, was published Oct. 14, 1847, one of Missouri's 10 oldest newspapers. It continues to publish. The railroad came in about 1867. Trains and Missouri River barges continue to move the products of this fertile land.

A group of prominent local men joined the California Gold Rush in 1849. Their stories are told in letters sent home by a man named Locke to his wife, who saved them. A book containing these letters is in the Brunswick Library.

Brunswick's potential as a future trading hub may have been diminished by bitterness, which divided citizens during the Civil War. This is illustrated by the passage from the 1883 History of Howard and Chariton Counties, which called the following excerpt a "curious memento."

"We, the undersigned citizens of Brunswick, pledge our sacred honor to maintain and defend the stars and stripes, which now float on what is now known as the Douglas pole ... If by accident, or otherwise, the same shall be destroyed, to erect another in its stead. We further pledge ourselves to protect ... the rights of both person and property of all Union men in our midst ... All the foregoing we solemnly pledge our honor to Lieutenant-Colonel Robert White shall be carried out in good faith." It was dated July 7, 186 1, and signed by A. Kennedy, mayor-, Frederick Sasse and John D Plunkett, councilmen; and P. R. Dolman, clerk. Despite this, Brunswick had many Southern sympathizers among its citizens, and many families owned slaves.

A significant contribution to Brunswick history occurred the night of March 10, 1914. Seven farmers had gathered around a pot-bellied stove in a one-room country school and began what became the Missouri Farmers Association.  Newcomer School is preserved as a monument to these men: Aaron Bachtel, Thomas Penick, John Kohl, Earl Smutz, Will Armstrong, and George and Will Heisel. 

In 1971, the Worthwhile Study Club, with help from most of the town's citizens, established the Brunswick Public Library. Soon someone discovered boxes of books from a 1930s library in the City Hall, and so the present library houses many books, both old and new. The crown jewel is probably two volumes about Indians, copyrighted in 1854.  They were in the Keytes family library and contain the founder's signature.

George and Elizabeth James helped Brunswick by promoting Brunswick as "The Pecan Capital of Missouri," by
discovering and patenting the Starking Hardy Giant pecan and by creating a pecan-hickory-nut cross, called a
"Hican."

Louis Kinkhorst, a Civil War veteran built an icehouse in Brunswick, stocked with ice cut from the Grand River. From this beginning, Kinkhorst and his son, Ludwig, launched businesses in coal delivery, ice making, individual cold storage lockers, soda bottling and beer distributing. The Brunswick Distributing Co. remains as one of Brunswick's major employers. 

Among Brunswick's once famous names were Bo Russell, world-renowned actor for whom the Russell Opera House on Broadway was named, and where he once performed; Wilbur Sweatman, world-famous jazz singer, once featured in Time magazine; the brilliant Dr. Cyrus W. Bowen, who for many years conducted a pharmacy school attended by students from all over the world.

Brunswick started as a river town. The rivers that sparked its beginnings and early growth all-too-frequently flooded, destroying millions of dollars worth of crops and property. Brunswick remains a village at the mercy of the mighty Missouri and the fickle Grand River. 

The Florence Hotel, built by a Mr. Keyte, began as a home around 1838. The southwest side of this home, near the street, was at one time used as a place for people to sell their wares. A Mrs. Sasse later purchased the home. She had the building enlarged and made it into the Florence Hotel. It has been a hotel well over 100 years. An outstanding feature is the louvered doors on the rooms. They helped provide air before air conditioners. There is a large fan on the second floor that was used and is still in use during the summer months. Air conditioners are now installed in each room. At one time there was a large dining area. It was converted into apartments a number of years ago.